Thomas R O'Brien Selected Research

Cytokines

11/2014	IFN-λ4: the paradoxical new member of the interferon lambda family.
6/2003	Haplotype diversity in the interleukin-4 gene is not associated with HIV-1 transmission and AIDS progression.

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Thomas R O'Brien Research Topics

Disease

21	Infections 12/2020 - 01/2003
12	Chronic Hepatitis C 01/2020 - 10/2008
8	Fibrosis (Cirrhosis) 11/2021 - 12/2007
6	Hepatitis C 09/2018 - 06/2009
5	Neoplasms (Cancer) 11/2019 - 03/2004
4	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 07/2011
4	Virus Diseases (Viral Diseases) 03/2020 - 06/2009
4	Acquired Immunodeficiency Syndrome (AIDS) 07/2010 - 12/2002
3	Liver Neoplasms (Liver Cancer) 01/2020 - 07/2006
3	Disease Progression 10/2017 - 02/2003
2	Liver Diseases (Liver Disease) 11/2021 - 05/2004
2	COVID-19 12/2020 - 01/2020
2	Hepatitis B 11/2019 - 07/2012
2	Communicable Diseases (Infectious Diseases) 10/2019 - 05/2008
2	Viremia 01/2018 - 07/2012
1	Chronic Hepatitis B 11/2021
1	HIV Infections (HIV Infection) 01/2020
1	Coinfection 01/2019
1	Hepatitis D 01/2018
1	Persistent Infection 01/2018
1	Ulcer 01/2015
1	Herpes Genitalis (Genital Herpes) 01/2015
1	Mannose-Binding Protein Deficiency 05/2008
1	Biliary Tract Neoplasms (Biliary Tract Cancer) 04/2008
1	Hepatitis 09/2007
1	Inflammation (Inflammations) 09/2006
1	Sepsis (Septicemia) 09/2006
1	Hypertension (High Blood Pressure) 01/2006
1	Varicella Zoster Virus Infection 03/2002

Drug/Important Bio-Agent (IBA)

9	Antiviral Agents (Antivirals)IBA 01/2020 - 03/2004
8	InterferonsIBA 12/2020 - 06/2009
8	RNA (Ribonucleic Acid)IBA 01/2019 - 05/2008
6	Interferon LambdaIBA 12/2020 - 10/2009
5	Ribavirin (Virazole)FDA LinkGeneric 06/2014 - 06/2009
5	Pharmaceutical PreparationsIBA 07/2012 - 03/2003
4	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2019 - 04/2008
3	DNA (Deoxyribonucleic Acid)IBA 01/2015 - 10/2008
3	Interferon-alpha (Interferon Alfa)IBA 06/2014 - 06/2009
3	HLA-B Antigens (HLA-B)IBA 07/2010 - 12/2002
2	Biomarkers (Surrogate Marker)IBA 11/2021 - 01/2021
2	DDTIBA 11/2019 - 07/2006
2	sofosbuvir drug combination ledipasvirIBA 04/2015 - 12/2014
2	AntibodiesIBA 01/2015 - 04/2008
2	CytokinesIBA 11/2014 - 06/2003
2	Caspase 12IBA 03/2007 - 09/2006
2	CCR5 Receptors (CCR5 Receptor)IBA 01/2006 - 01/2003
2	Chemokine ReceptorsIBA 01/2006 - 02/2003
1	Interleukin-8 (Interleukin 8)IBA 11/2021
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	Alanine Transaminase (SGPT)IBA 01/2020
1	Triglycerides (Triacylglycerol)IBA 01/2020
1	oxidized low density lipoproteinIBA 01/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2020
1	Polychlorinated Biphenyls (PCBs)IBA 01/2020
1	HDL LipoproteinsIBA 01/2020
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020
1	InsecticidesIBA 11/2019
1	Chlordan (Chlordane)IBA 11/2019
1	nonachlorIBA 11/2019
1	oxychlordaneIBA 11/2019
1	Biological ProductsIBA 10/2019
1	Aflatoxin B1 (Aflatoxin B)IBA 01/2019
1	HLA-B57 antigenIBA 10/2017
1	SofosbuvirIBA 06/2014
1	Protease Inhibitors (Protease Inhibitor)IBA 06/2014
1	Double-Stranded RNA (RNA, Double Stranded)IBA 02/2013
1	EnzymesIBA 07/2012
1	Epidermal Growth Factor (EGF)IBA 07/2011
1	Protein Isoforms (Isoforms)IBA 07/2010
1	Recombinant ProteinsIBA 07/2010
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 05/2008
1	Surface Antigens (Surface Antigen)IBA 04/2008
1	AntigensIBA 04/2008
1	N-acetyltalosaminuronic acid (NAT)IBA 02/2008
1	Enzyme Precursors (Zymogens)IBA 09/2006
1	CaspasesIBA 09/2006
1	Dichlorodiphenyl Dichloroethylene (DDE)IBA 07/2006
1	CCR ReceptorsIBA 01/2006
1	Circular DNAIBA 05/2004
1	Interleukin-4 (Interleukin 4)IBA 06/2003
1	A 19IBA 02/2003
1	Immunoglobulin G (IgG)IBA 03/2002

Therapy/Procedure

6	Therapeutics 01/2020 - 06/2009
1	Duration of Therapy 11/2017